Granulomatosis with Polyangiitis: A Case Report

Abstract

Granulomatosis with polyangiitis is a rare and idiopathic systemic vasculitis characterized by the reaching of small and medium vessels. The disease affects, preferably, the upper and lower airways and the kidneys, leading to the formation of granulomas and necrosis of these organs. Clinical manifestations and organic involvement are very variable. Diagnosis and treatment are critical and delay in diagnosis can be fatal. The authors present the case of a male patient, with an atypical presentation, where involvement of the respiratory and cerebral tract has been documented, but with a favorable evolution after diagnosis and adequate treatment. In this work we intend to review the disease, forms of presentation, diagnostic criteria, therapeutic approach, and prognostic.