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Abstract

Sclerosing cholangitis refers to a group of liver diseases characterized by inflammation and fibrosis of the bile ducts, which can lead to cirrhosis and liver failure. It is divided into two forms: primary, usually associated with inflammatory bowel disease, and secondary, caused by external factors.
Secondary sclerosing cholangitis associated with critically ill patients is a cholestatic disease that occurs in patients without known hepatobiliary pathology after admission to an Intensive Care Unit.
We present the case of a 55-year-old male patient admitted to the Intensive Care Unit due to septic shock associated with respiratory failure. During hospitalization, he developed abnormal liver enzyme levels, and magnetic resonance cholangiopancreatography and liver biopsy supported the diagnosis of secondary sclerosing cholangitis associated with critical illness.
This condition is of particular interest as it is associated with high morbidity and mortality, in addition to having a significant impact on the therapeutic management of patients.