Severe Thrombocytopenia Caused by Piperacillin/Tazobactam: A Case Report

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Sara Montezinho - Corresponding Author

Sara Montezinho [saramontezinho@gmail.com]
Rua Dr. Cândido Pinho 5, 4520-211 Santa Maria da Feira, Portugal
ORCID iD: 0000-0003-0505-8925

Miguel Oliveira
Manuela Alves

Abstract

Thrombocytopenia is a recognized side effect of various medications, beverages, foods, and herbal remedies. Piperacillin/tazobactam is a beta-lactam/beta-lactamase inhibitor combination with a broad spectrum of antibacterial activity, associated with hematologic adverse such as reversible neutropenia, but Coombs-positive hemolytic anemia and thrombocytopenia are also reported. We report a case of a 73-year-old male patient with severe piperacillin/tazobactam induced thrombocytopenia
later confirmed due to re-exposure to the drug.

Keywords: Piperacillin, Tazobactam Drug Combination/adverse effects; Thrombocytopenia/chemically induced

Article Details

Montezinho, S., Oliveira, M., & Alves, M. (2021). Severe Thrombocytopenia Caused by Piperacillin/Tazobactam: A Case Report. Gazeta Médica, 8(1). https://doi.org/10.29315/gm.v8i1.382
Section
CLINICAL CASE