Testicular Germ Cell Tumours: Casuistics in Hospital CUF Infante Santo Tumores de Células Germinativas Testiculares: Casuística do Hospital CUF Infante Santo

Abstract

INTRODUCTION: Germ cell tumors are rare tumors, accounting for 1% to 2% of all malignancies and about 5% of all malignant urologic tumors. They originate in the testis in more than 90% of cases.
METHODS: The authors conduct a review of all cases of germ cell tumors, from diagnose and treatment till follow-up, treated in Hospital CUF Infante Santo comprising a period of more than 15 years, between 1999 August and 2014 November.
RESULTS: This series include 33 patients all of them submitted to diagnostic and therapeutic radical orchiectomy, with the majority of them in clinical stage I disease: 21 patients (63.6%). Of this early stage patients, 14 (66%), later received post surgical treatment. All the patients with more advanced stages where submitted to treatment post orchiectomy. There were four recurrences (12.1%), at a median time of 20 months post diagnose and all of them achieved a second complete remission after treatment.
CONCLUSION: Overall the toxicity seems acceptable, not registering any death as a secondary effect of any kind of treatment. At the conclusion of this revue, with a median follow-up of 59 months, all patients were alive and free from disease.